A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups).
Chemical ID:
MESH:D002945
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Cisplatin results in increased expression of CASP3 mRNA; Cisplatin results in increased expression of CASP3 protein; Cisplatin results in increased expression of CASP3 protein modified form
(+)-JQ1 compound promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Eicosapentaenoic Acid promotes the reaction [Cisplatin results in increased activity of CASP3 protein]]; 8-(4-chloro-phenylthio)-2'-O-methyladenosine-3'-5'-cyclic monophosphate inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]; [3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [FAM168A results in decreased susceptibility to Cisplatin]] which results in increased cleavage of CASP3 protein; [4-methylene-2-octyl-5-oxofuran-3-carboxylic acid co-treated with Cisplatin] results in increased cleavage of and results in decreased expression of CASP3 protein; [4-methylene-2-octyl-5-oxofuran-3-carboxylic acid co-treated with Cisplatin] results in increased cleavage of and results in increased activity of CASP3 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of CASP3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of CASP3 protein; [ACE2 protein inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]] which results in decreased cleavage of PARP1 protein; [andrographolide co-treated with Cisplatin] results in increased expression of CASP3 mRNA; [Berberine co-treated with Cisplatin] results in increased cleavage of CASP3 protein; [Cisplatin co-treated with Bortezomib] results in increased activity of CASP3 protein; [Cisplatin co-treated with CDKN1A protein] results in increased cleavage of CASP3 protein; [Cisplatin co-treated with chrysin] results in increased cleavage of CASP3 protein; [Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein; [Cisplatin co-treated with fisetin] results in increased cleavage of and results in increased activity of CASP3 protein; [Cisplatin co-treated with Roflumilast] results in increased expression of CASP3 mRNA; [Cisplatin co-treated with S63845] results in increased cleavage of CASP3 protein; [Cisplatin promotes the reaction [TNFSF10 protein results in increased cleavage of and results in increased activity of CASP3 protein]] which results in increased cleavage of XIAP protein; [Cisplatin results in decreased susceptibility to Cisplatin] which results in increased expression of CASP3 mRNA; [Cisplatin results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein; [CITED2 results in decreased susceptibility to Cisplatin] which results in decreased activity of CASP3 protein; [Fluorouracil co-treated with Cisplatin] results in increased activity of CASP3 protein; [Fluorouracil co-treated with Cisplatin] results in increased expression of CASP3 protein; [GJB1 protein co-treated with GJB2 protein] promotes the reaction [Cisplatin results in increased activity of CASP3 protein]; [Noscapine co-treated with Cisplatin] results in increased cleavage of CASP3 protein; [Paclitaxel co-treated with Cisplatin] results in increased activity of CASP3 protein; [Quercetin co-treated with Cisplatin] results in increased activity of CASP3 protein; [S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of CASP3 protein; [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; [SLC39A8 protein affects the susceptibility to Cisplatin] which affects the cleavage of CASP3 protein; [SND1 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of and results in increased activity of CASP3 protein; [TNFSF10 protein co-treated with Cisplatin] results in increased activity of CASP3 protein; [trigonelline co-treated with Cisplatin] results in increased cleavage of CASP3 protein; ABCB1 protein inhibits the reaction [Cisplatin results in increased activity of and results in increased cleavage of CASP3 protein]; acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [[GJB1 protein co-treated with GJB2 protein] promotes the reaction [Cisplatin results in increased activity of CASP3 protein]]; acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Berberine co-treated with Cisplatin] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]]; Acetylcysteine inhibits the reaction [Cisplatin promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]]; Acetylcysteine inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; AKT1 protein inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Arsenic Trioxide promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]; astilbin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; BCL2 inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; BCL2 protein inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cisplatin co-treated with chrysin] results in increased cleavage of CASP3 protein]; beta-solamarine promotes the reaction [Cisplatin results in increased activity of CASP3 protein]; BMI1 protein inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; calpeptin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; CAPN1 protein affects the reaction [Cisplatin results in increased cleavage of CASP3 protein]; CAPN2 protein affects the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Carbidopa inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; CAV1 protein promotes the reaction [Cisplatin results in increased activity of CASP3 protein]; CD40LG protein inhibits the reaction [Cisplatin promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; Chloroquine promotes the reaction [Cisplatin results in increased expression of CASP3 protein]; Cisplatin inhibits the reaction [Oleanolic Acid results in increased cleavage of CASP3 protein]; Cisplatin promotes the reaction [(+)-JQ1 compound results in increased cleavage of CASP3 protein]; Cisplatin promotes the reaction [5-((2,6-dichlorobenzyl)sulfonyl)-3-((3,5-dimethyl-4-((2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-1,3-dihydro-2H-indol-2-one results in increased cleavage of CASP3 protein]; Cisplatin promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Cisplatin promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]; Cisplatin promotes the reaction [eprenetapopt results in increased cleavage of CASP3 protein]; Cisplatin promotes the reaction [Metformin results in increased activity of CASP3 protein]; Cisplatin promotes the reaction [Roflumilast results in increased activity of CASP3 protein]; Cisplatin promotes the reaction [Roflumilast results in increased expression of CASP3 mRNA]; Cisplatin promotes the reaction [S63845 results in increased cleavage of CASP3 protein]; Cisplatin promotes the reaction [SC-66 compound results in increased cleavage of CASP3 protein]; Cisplatin promotes the reaction [TNFSF10 protein results in increased cleavage of and results in increased activity of CASP3 protein]; Cisplatin results in decreased expression of and results in increased cleavage of CASP3 protein; Cisplatin results in increased activity of and results in increased cleavage of CASP3 protein; Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein; Cisplatin results in increased expression of and results in increased cleavage of CASP3 protein; CITED2 mutant form promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]; CXCL8 inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Deferoxamine inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; DICER1 mutant form inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Eicosapentaenoic Acid promotes the reaction [Cisplatin results in increased activity of CASP3 protein]; ESR2 protein promotes the reaction [Cisplatin results in increased expression of CASP3 protein]; FAM168A protein inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; GCS-100 promotes the reaction [Cisplatin results in increased activity of CASP3 protein]; GJA1 protein affects the reaction [Cisplatin results in increased cleavage of CASP3 protein]; GNAS protein inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Hemin promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]; hesperetin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; HMGN5 protein inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; HSPA5 protein affects the reaction [Cisplatin results in increased cleavage of CASP3 protein]; IER5 protein promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]; ING4 protein promotes the reaction [Cisplatin results in increased activity of CASP3 protein]; Inositol inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; MAF1 protein affects the reaction [Cisplatin results in increased cleavage of CASP3 protein]; MIR630 mRNA inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Nicotine inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Noscapine promotes the reaction [Cisplatin results in increased expression of and results in increased cleavage of CASP3 protein]; Oleanolic Acid inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; oleylamide inhibits the reaction [[GJB1 protein co-treated with GJB2 protein] promotes the reaction [Cisplatin results in increased activity of CASP3 protein]]; Omeprazole inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Oxygen deficiency promotes the reaction [Cisplatin promotes the reaction [eprenetapopt results in increased cleavage of CASP3 protein]]; PD 150606 inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; PD 150606 inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; PLK1 protein inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; PRDX6 protein inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; RAPGEF3 affects the reaction [8-(4-chloro-phenylthio)-2'-O-methyladenosine-3'-5'-cyclic monophosphate inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]]; RELA protein mutant form inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; RNF34 protein inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Roflumilast promotes the reaction [Cisplatin results in increased activity of CASP3 protein]; sarpogrelate inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; SC-66 compound promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Sirolimus promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]; SMG1 protein inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; SND1 mutant form promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]; TNFSF10 protein promotes the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]; TP53 protein affects the reaction [Cisplatin results in increased cleavage of CASP3 protein]; TRAF2 protein affects the reaction [Cisplatin results in increased cleavage of CASP3 protein]; TRAP1 protein inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]; Tretinoin promotes the reaction [[GJB1 protein co-treated with GJB2 protein] promotes the reaction [Cisplatin results in increased activity of CASP3 protein]]; TYMP inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; TYMP protein inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; USP39 protein inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]; Valproic Acid promotes the reaction [Cisplatin results in increased activity of CASP3 protein]; YAP1 protein inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; zinc protoporphyrin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]
Cisplatin results in increased expression of CASP3 mRNA; Cisplatin results in increased expression of CASP3 protein; Cisplatin results in increased expression of CASP3 protein modified form
Cisplatin results in increased expression of CASP3; Cisplatin results in increased expression of CASP3 mRNA; Cisplatin results in increased expression of CASP3 protein; Cisplatin results in increased expression of CASP3 protein modified form
2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]]; 8-(4-chloro-phenylthio)-2'-O-methyladenosine-3'-5'-cyclic monophosphate inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]; [5-aminoisoquinoline co-treated with Cisplatin] results in increased expression of CASP3 protein; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]; [Cisplatin co-treated with Vinorelbine] results in increased activity of CASP3 protein; [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; [SLC39A8 protein results in increased susceptibility to Cisplatin] which results in increased cleavage of CASP3 protein; ABCB1 protein inhibits the reaction [Cisplatin results in increased activity of and results in increased cleavage of CASP3 protein]; acetovanillone inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]; anemoside B4 inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; apelin-13 peptide inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; arachidonyl-2-chloroethylamide inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Aspirin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; ATG7 gene mutant form inhibits the reaction [trichostatin A inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]]; ATG7 gene mutant form inhibits the reaction [trichostatin A inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]]; aucubin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; CARM1 protein affects the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Carnosine inhibits the reaction [Cisplatin results in increased expression of and results in increased cleavage of CASP3 protein]; Carvedilol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]; Catechin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; CDKN1A protein inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Chlorogenic Acid inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Chloroquine inhibits the reaction [trichostatin A inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]]; Chloroquine promotes the reaction [Cisplatin results in increased expression of CASP3 protein modified form]; Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein; Cisplatin results in increased cleavage of and results in increased expression of CASP3 protein; Cisplatin results in increased expression of and results in increased cleavage of CASP3 protein; coenzyme Q10 inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; Colforsin inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]; cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; erdosteine inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; hesperetin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; IL6 inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Imatinib Mesylate inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Inositol inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Isoproterenol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]; Linagliptin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Luteolin inhibits the reaction [Cisplatin results in increased cleavage of and results in increased expression of CASP3 protein]; madecassoside inhibits the reaction [Cisplatin results in increased expression of and results in increased cleavage of CASP3 protein]; MAP2K1 protein promotes the reaction [Cisplatin results in increased activity of CASP3 protein]; Melatonin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]; Metoclopramide inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Oleanolic Acid inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; PAK2 protein modified form promotes the reaction [Cisplatin results in increased activity of CASP3 protein]; PARK7 protein affects the reaction [Cisplatin results in increased cleavage of CASP3 protein]; pevonedistat inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; pevonedistat inhibits the reaction [Cisplatin results in increased expression of CASP3 mRNA]; pifithrin inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]]]; PRMT3 protein affects the reaction [Cisplatin results in increased cleavage of CASP3 protein]; RAPGEF3 mutant form inhibits the reaction [Isoproterenol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]]; Resveratrol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]; Rosmarinic Acid inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Rutin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; salubrinal promotes the reaction [Cisplatin results in increased activity of CASP3 protein]; salubrinal promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]; sarpogrelate inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; SIRT3 protein promotes the reaction [Metformin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]]; Sodium Acetate inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Streptozocin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; Thioctic Acid inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; TIMD2 promotes the reaction [Cisplatin results in increased expression of CASP3 protein modified form]; trichostatin A inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; trichostatin A inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]
2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [Cisplatin results in increased expression of CASP3 mRNA]; 5,10,15,20-tetrakis(N-methyl-4'-pyridyl)porphyrinato-iron(III) inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; [epigallocatechin gallate co-treated with coenzyme Q10] inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; acetovanillone inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; astragaloside A inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; Carvedilol inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Chloroquine inhibits the reaction [trichostatin A inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]]; Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein; Cisplatin results in increased expression of and results in increased activity of CASP3 protein; CTNNA1 gene affects the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]; cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [Cisplatin results in increased expression of CASP3]; Eicosanoids analog inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; fisetin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; formononetin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]; HNF1B protein inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]; Melatonin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Metformin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 mRNA]; MIR375 mRNA promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]; montelukast inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; naringin inhibits the reaction [Cisplatin results in increased expression of CASP3 mRNA]; Pravastatin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; Resveratrol inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Roflumilast inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Roflumilast inhibits the reaction [Cisplatin results in increased expression of CASP3 mRNA]; SB 203580 promotes the reaction [Cisplatin results in increased activity of CASP3 protein]; Sildenafil Citrate inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Silymarin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; Sodium Acetate inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Tadalafil inhibits the reaction [Cisplatin results in increased expression of CASP3 mRNA]; tangeretin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; trichostatin A inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; vanillin inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Venlafaxine Hydrochloride inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; wogonin inhibits the reaction [Cisplatin results in increased expression of and results in increased activity of CASP3 protein]; zinc protoporphyrin inhibits the reaction [Tadalafil inhibits the reaction [Cisplatin results in increased expression of CASP3 mRNA]]
