GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CASP3 | increases activity | ISO | Casp3 (Rattus norvegicus) | 6480464 | CTD | 2-Acetylaminofluorene results in increased activity of CASP3 protein | PMID:23665045 | CASP3 | increases expression | ISO | Casp3 (Rattus norvegicus) | 6480464 | CTD | 2-Acetylaminofluorene results in increased expression of CASP3 protein | PMID:26364502 | CASP3 | multiple interactions | ISO | Casp3 (Rattus norvegicus) | 6480464 | CTD | 2-Acetylaminofluorene inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased cleavage of CASP3 protein]; Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of CASP3 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of CASP3 protein] | PMID:12907702 PMID:23665045 PMID:26364502 | |
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