Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731002
Species: Homo sapiens
RGD Object: Gene
Symbol: CASP3
Name: caspase 3
Acc ID: CHEBI:16347
Term: (R)-carnitine
Definition: The (R)-enantiomer of carnitine.
Chemical ID: MESH:D002331
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP3multiple interactionsEXP 6480464CTDCarnitine inhibits the reaction [quinone results in increased activity of CASP3 protein]PMID:32478940
CASP3multiple interactionsISOCasp3 (Rattus norvegicus)6480464CTDCarnitine inhibits the reaction [Atrazine results in increased expression of CASP3 mRNA]; Carnitine inhibits the reaction [Gentamicins results in increased cleavage of CASP3 protein]; Carnitine inhibits the reaction [Ifosfamide results in increased expression of CASP3 mRNA]; Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of CASP3 mRNA]]; Carnitine inhibits the reaction [Methotrexate results in increased expression of CASP3 protein]PMID:19491382 PMID:23213347 PMID:26562095 PMID:36282381 PMID:37312617
Go Back to source page   Continue to Ontology report