GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hsf1 | increases activity | ISO | HSF1 (Homo sapiens) | 6480464 | CTD | Resveratrol results in increased activity of HSF1 protein | PMID:34170685 | Hsf1 | multiple interactions | ISO | HSF1 (Homo sapiens) | 6480464 | CTD | [resveratrol results in decreased phosphorylation of GSK3B protein] which results in decreased expression of HSF1 mRNA; [resveratrol results in increased activity of GSK3B protein] which results in decreased expression of HSF1 mRNA; resveratrol inhibits the reaction [Cadmium Chloride results in decreased phosphorylation of HSF1 protein]; resveratrol inhibits the reaction [sodium arsenite results in decreased phosphorylation of HSF1 protein]; resveratrol results in decreased localization of and results in decreased activity of HSF1 protein | PMID:18429957 PMID:20090934 PMID:24412756 | | ||||||||||||||||||||||
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