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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730988
Species: Homo sapiens
RGD Object: Gene
Symbol: VCAM1
Name: vascular cell adhesion molecule 1
Acc ID: CHEBI:50686
Term: atorvastatin calcium
Definition: An organic calcium salt composed of calcium cations and atorvastatin anions in a 1:2 ratio.
Chemical ID: MESH:D000069059
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
VCAM1decreases expressionEXP 6480464CTDAtorvastatin results in decreased expression of VCAM1 mRNA; Atorvastatin results in decreased expression of VCAM1 proteinPMID:17673219 PMID:22245985
VCAM1multiple interactionsISOVcam1 (Rattus norvegicus)6480464CTDAtorvastatin inhibits the reaction [sodium arsenite results in increased expression of VCAM1 protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]PMID:17589825 PMID:25058445
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