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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730988
Species: Homo sapiens
RGD Object: Gene
Symbol: VCAM1
Name: vascular cell adhesion molecule 1
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
VCAM1multiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]PMID:12615669 PMID:19281832 PMID:25876056 PMID:26901245 PMID:35349355
VCAM1multiple interactionsISOVcam1 (Mus musculus)6480464CTDAcetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of VCAM1 protein]]PMID:19642688
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