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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730988
Species: Homo sapiens
RGD Object: Gene
Symbol: VCAM1
Name: vascular cell adhesion molecule 1
Acc ID: CHEBI:17230
Term: homocysteine
Definition: A sulfur-containing amino acid consisting of a glycine core with a 2-mercaptoethyl side-chain.
Chemical ID: MESH:D006710
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
VCAM1increases expressionEXP 6480464CTDHomocysteine results in increased expression of VCAM1 mRNA; Homocysteine results in increased expression of VCAM1 proteinPMID:17586618
VCAM1multiple interactionsEXP 6480464CTD3,4-dihydroxyphenylethanol inhibits the reaction [Homocysteine results in increased expression of VCAM1 protein]; resveratrol inhibits the reaction [Homocysteine results in increased expression of VCAM1 protein]PMID:17586618
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