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GENE - TERM ANNOTATION REPORT

RGD ID: 730981
Species: Homo sapiens
RGD Object: Gene
Symbol: IL1B
Name: interleukin 1 beta
Acc ID: DOID:9005372
Term: Inflammation
Definition: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
Definition Source(s): MESH:D007249
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL1B ISOIl1b (Rattus norvegicus)1626645RGDassociated with Cholestasis;mRNA:increased expression:liver 
IL1B ISOIl1b (Rattus norvegicus)1626679RGDassociated with Hypersensitivity, Delayed;protein:increased expression:brain, plasma 
IL1B ISOIl1b (Rattus norvegicus)7204492RGDassociated with Anoxia 
IL1BtreatmentISOIl1b (Rattus norvegicus)11059519RGD  
IL1BtreatmentISOIl1b (Rattus norvegicus)11059520RGD  
IL1B EXP 11554173CTDCTD Direct Evidence: marker/mechanismPMID:9952427 PMID:11181422 PMID:16227999 PMID:21437948 PMID:21467745 PMID:22001142 PMID:23640035 PMID:24609059 PMID:28212736
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