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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730972
Species: Homo sapiens
RGD Object: Gene
Symbol: SREBF2
Name: sterol regulatory element binding transcription factor 2
Acc ID: CHEBI:34202
Term: 2,2',4,4',5,5'-hexachlorobiphenyl
Definition: A hexachlorobiphenyl that has formula C12H4Cl6.
Chemical ID: MESH:C014024
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SREBF2decreases expressionISOSrebf2 (Mus musculus)6480464CTD2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of SREBF2 mRNAPMID:20005886 PMID:21851831
SREBF2multiple interactionsISOSrebf2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of SREBF2 mRNA]PMID:21851831
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