GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tgfb2 | increases expression | EXP | | 6480464 | CTD | troglitazone results in increased expression of TGFB2 mRNA | PMID:17569031 | Tgfb2 | decreases response to substance | ISO | TGFB2 (Homo sapiens) | 6480464 | CTD | troglitazone results in decreased susceptibility to TGFB2 protein | PMID:18253093 | Tgfb2 | increases expression | ISO | Tgfb2 (Rattus norvegicus) | 6480464 | CTD | troglitazone results in increased expression of TGFB2 mRNA | PMID:21515302 | Tgfb2 | multiple interactions | ISO | TGFB2 (Homo sapiens) | 6480464 | CTD | troglitazone inhibits the reaction [TGFB2 protein results in increased expression of COL1A1 mRNA]; troglitazone inhibits the reaction [TGFB2 protein results in increased expression of FN1 mRNA]; troglitazone inhibits the reaction [TGFB2 protein results in increased expression of FN1 protein]; troglitazone inhibits the reaction [TGFB2 protein results in increased phosphorylation of and affects the localization of SMAD2 protein]; troglitazone inhibits the reaction [TGFB2 protein results in increased phosphorylation of and affects the localization of SMAD3 protein] | PMID:18253093 | | ||||||||||||||||||||||
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