GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HIF1A | increases degradation | EXP | | 6480464 | CTD | Minocycline results in increased degradation of HIF1A protein | PMID:24292262 | HIF1A | multiple interactions | EXP | | 6480464 | CTD | [[Minocycline promotes the reaction [HIF1A protein binds to VHL protein]] co-treated with [Minocycline results in increased expression of EGLN1 protein]] inhibits the reaction [Oxygen deficiency results in increased stability of HIF1A protein]; [[Minocycline promotes the reaction [HIF1A protein binds to VHL protein]] co-treated with [Minocycline results in increased expression of EGLN1 protein]] results in increased degradation of HIF1A protein; Minocycline inhibits the reaction [Oxygen deficiency results in increased stability of HIF1A protein]; Minocycline promotes the reaction [HIF1A protein binds to VHL protein] | PMID:24292262 | | ||||||||||||||||||||||
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