GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HIF1A | affects expression | EXP | | 6480464 | CTD | Arsenic Trioxide affects the expression of HIF1A mRNA | PMID:20458559 | HIF1A | decreases expression | EXP | | 6480464 | CTD | Arsenic Trioxide results in decreased expression of HIF1A; Arsenic Trioxide results in decreased expression of HIF1A mRNA; Arsenic Trioxide results in decreased expression of HIF1A protein | PMID:19769630 PMID:25047463 PMID:25088040 PMID:34108876 | HIF1A | increases expression | EXP | | 6480464 | CTD | Arsenic Trioxide results in increased expression of HIF1A protein | PMID:12482858 PMID:29396848 | HIF1A | multiple interactions | EXP | | 6480464 | CTD | [Oxygen deficiency co-treated with Arsenic Trioxide] results in increased expression of HIF1A protein; Arsenic Trioxide promotes the reaction [cobaltous chloride results in increased expression of HIF1A protein]; Arsenic Trioxide promotes the reaction [Deferoxamine results in increased expression of HIF1A protein] | PMID:16330433 PMID:19825857 | HIF1A | increases expression | ISO | Hif1a (Mus musculus) | 6480464 | CTD | Arsenic Trioxide results in increased expression of HIF1A protein | PMID:15888669 | |
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