GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HIF1A | affects expression | EXP | | 6480464 | CTD | resveratrol affects the expression of HIF1A protein | PMID:17473185 | HIF1A | decreases expression | EXP | | 6480464 | CTD | resveratrol results in decreased expression of HIF1A; resveratrol results in decreased expression of HIF1A mRNA; resveratrol results in decreased expression of HIF1A protein | PMID:12002526 PMID:15297429 PMID:19828106 PMID:23314035 | HIF1A | increases degradation | EXP | | 6480464 | CTD | resveratrol results in increased degradation of HIF1A protein | PMID:15297429 PMID:17919812 | HIF1A | increases expression | EXP | | 6480464 | CTD | resveratrol results in increased expression of HIF1A protein | PMID:22245592 | HIF1A | multiple interactions | EXP | | 6480464 | CTD | [Resveratrol results in increased activity of SIRT1 protein] which results in increased expression of HIF1A protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; Resveratrol inhibits the reaction [2,2'-Dipyridyl results in increased expression of HIF1A protein]; Resveratrol inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; Resveratrol inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]; Resveratrol inhibits the reaction [Dinoprostone results in increased expression of and results in increased acetylation of HIF1A protein]; Resveratrol inhibits the reaction [HIF1A protein results in increased activity of AR protein]; Resveratrol inhibits the reaction [IGF1 protein results in increased expression of HIF1A protein]; Resveratrol inhibits the reaction [INS protein results in increased expression of HIF1A protein]; Resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of HIF1A protein]; Resveratrol inhibits the reaction [Oxygen deficiency affects the localization of HIF1A protein]; Resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Resveratrol results in decreased expression of and affects the localization of HIF1A protein; Resveratrol results in increased ubiquitination of and results in increased degradation of HIF1A protein; SIRT1 protein promotes the reaction [Resveratrol inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]] | PMID:15297429 PMID:16227395 PMID:17919812 PMID:18674879 PMID:20153296 PMID:22245592 PMID:24975222 PMID:25297617 PMID:25815440 PMID:26174951 PMID:30409902 | HIF1A | decreases expression | ISO | Hif1a (Rattus norvegicus) | 6480464 | CTD | resveratrol results in decreased expression of HIF1A protein | PMID:22050707 | HIF1A | decreases expression | ISO | Hif1a (Mus musculus) | 6480464 | CTD | resveratrol results in decreased expression of HIF1A protein | PMID:24221993 | HIF1A | multiple interactions | ISO | Hif1a (Rattus norvegicus) | 6480464 | CTD | [resveratrol co-treated with plastochromanol 8] results in decreased expression of HIF1A protein; resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A mRNA]; resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A protein]; resveratrol inhibits the reaction [Glucose results in increased expression of HIF1A mRNA]; resveratrol inhibits the reaction [Glucose results in increased expression of HIF1A protein]; resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]; SIRT1 protein affects the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of HIF1A protein]] | PMID:21914476 PMID:22050707 PMID:23421680 PMID:26891083 | HIF1A | multiple interactions | ISO | Hif1a (Mus musculus) | 6480464 | CTD | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in decreased expression of HIF1A protein]; resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of HIF1A protein]; resveratrol inhibits the reaction [Nicotine results in decreased expression of HIF1A mRNA] | PMID:22687363 PMID:24221993 PMID:26074695 | |
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