GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HMOX1 | decreases expression | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | Bleomycin results in decreased expression of HMOX1 protein | PMID:26768587 | HMOX1 | increases expression | ISO | Hmox1 (Mus musculus) | 6480464 | CTD | Bleomycin results in increased expression of HMOX1 protein | PMID:16317386 | HMOX1 | increases expression | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | Bleomycin results in increased expression of HMOX1 mRNA | PMID:26093215 | HMOX1 | multiple interactions | ISO | Hmox1 (Mus musculus) | 6480464 | CTD | PPARA protein affects the reaction [Bleomycin results in increased expression of HMOX1 protein] | PMID:16317386 | HMOX1 | multiple interactions | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | celastrol inhibits the reaction [Bleomycin results in decreased expression of HMOX1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA] | PMID:26093215 PMID:26768587 | |
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