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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730895
Species: Mus musculus
RGD Object: Gene
Symbol: Il18
Name: interleukin 18
Acc ID: CHEBI:34718
Term: 1-chloro-2,4-dinitrobenzene
Definition: A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Chemical ID: MESH:D004137
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il18increases activityEXP 6480464CTDDinitrochlorobenzene results in increased activity of IL18 proteinPMID:15840424
Il18increases expressionEXP 6480464CTDDinitrochlorobenzene results in increased expression of IL18 mRNAPMID:11708898
Il18increases expressionISOIL18 (Homo sapiens)6480464CTDDinitrochlorobenzene results in increased expression of IL18 proteinPMID:23063874 PMID:27585668 PMID:28389280
Il18multiple interactionsISOIL18 (Homo sapiens)6480464CTDPRDM1 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of IL18 protein]PMID:27585668
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