GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfkb1 | multiple interactions | EXP | | 6480464 | CTD | [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NFKB1 protein; Glucose results in increased activity of and affects the localization of NFKB1 protein; INO 1001 inhibits the reaction [Glucose results in increased activity of and affects the localization of NFKB1 protein]; NFKB1 protein inhibits the reaction [SOD1 protein promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of PTGS2 protein]]; SOD1 protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of and results in increased activity of NFKB1 protein] | PMID:16395278 PMID:17065336 | Nfkb1 | increases expression | ISO | NFKB1 (Homo sapiens) | 6480464 | CTD | Glucose results in increased expression of NFKB1 mRNA; Glucose results in increased expression of NFKB1 protein | PMID:18180316 PMID:21682256 | Nfkb1 | multiple interactions | ISO | NFKB1 (Homo sapiens) | 6480464 | CTD | [Glucose results in increased susceptibility to sodium arsenite] which results in increased expression of NFKB1 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NFKB1 mRNA; Polyphenols inhibits the reaction [Glucose results in increased expression of NFKB1 mRNA] | PMID:21682256 PMID:28264687 PMID:32613381 | |
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