An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Chemical ID:
MESH:D010269
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
[Paraquat co-treated with SOD2 protein] results in increased cleavage of LMNB1 protein; [Paraquat co-treated with SOD2 protein] results in increased expression of FOS mRNA; [Paraquat co-treated with SOD2 protein] results in increased expression of JUN mRNA; [Paraquat co-treated with SOD2 protein] results in increased expression of MMP1 mRNA; [Paraquat results in increased activity of SOD2 protein] which results in decreased expression of ICAM1 protein; IL1A protein promotes the reaction [Paraquat results in increased expression of SOD2 protein]; IL1B protein promotes the reaction [Paraquat results in increased expression of SOD2 protein]; Plant Extracts inhibits the reaction [Paraquat results in decreased expression of SOD2 mRNA]; SOD2 protein promotes the reaction [Paraquat results in increased chemical synthesis of and results in increased secretion of Hydrogen Peroxide]; TNF protein promotes the reaction [Paraquat results in increased expression of SOD2 protein]
[Maneb co-treated with Paraquat] results in decreased expression of SOD2 protein; [MTHFR gene polymorphism affects the susceptibility to Paraquat] which results in increased expression of SOD2 protein; [TRP53 protein results in decreased expression of SOD2 mRNA] which results in increased susceptibility to Paraquat; APOD protein affects the reaction [Paraquat results in increased expression of SOD2 mRNA]; Dapsone inhibits the reaction [Paraquat results in decreased expression of SOD2 protein]; EPO protein inhibits the reaction [SOD2 gene mutant form results in increased susceptibility to Paraquat]; Levodopa inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of SOD2 protein]; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of SOD2 protein]; Oxygen affects the reaction [SOD2 gene mutant form affects the susceptibility to Paraquat]; Paraquat affects the reaction [APOD protein affects the expression of SOD2 protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of SOD2 protein]
[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of SOD2 mRNA; Dexamethasone inhibits the reaction [Paraquat results in increased activity of SOD2 protein]; SB 203580 inhibits the reaction [[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of SOD2 mRNA]; Verapamil inhibits the reaction [Dexamethasone inhibits the reaction [Paraquat results in increased activity of SOD2 protein]]
