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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730871
Species: Homo sapiens
RGD Object: Gene
Symbol: PRLR
Name: prolactin receptor
Acc ID: CHEBI:3374
Term: capsaicin
Definition: A capsaicinoid that has formula C18H27NO3.
Chemical ID: MESH:D002211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PRLRincreases expressionISOPrlr (Rattus norvegicus)6480464CTDCapsaicin results in increased expression of PRLR proteinPMID:22150557
PRLRmultiple interactionsISOPrlr (Rattus norvegicus)6480464CTD[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of PRLR protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of PRLR protein]; Sumatriptan affects the reaction [Capsaicin results in increased expression of PRLR protein]PMID:22150557
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