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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730858
Species: Homo sapiens
RGD Object: Gene
Symbol: IL2
Name: interleukin 2
Acc ID: CHEBI:34591
Term: bromodichloromethane
Definition: A halomethane that is dichloromethane in which oneof the hydrogens has been replaced by a bromine atom. It occurs as a contaminant in drinking water.
Chemical ID: MESH:C025191
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL2multiple interactionsISOIl2 (Mus musculus)6480464CTD[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL2 mRNA; [PRF1 protein co-treated with RAG2 protein] affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL2 mRNA]; CYP2E1 protein affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL2 mRNA]PMID:24211274
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