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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730855
Species: Homo sapiens
RGD Object: Gene
Symbol: SOD1
Name: superoxide dismutase 1
Acc ID: CHEBI:8708
Term: quetiapine fumarate
Definition: A fumarate salt that has formula (C21H25N3O2S)2.C4H4O4.
Chemical ID: MESH:D000069348
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SOD1increases expressionISOSod1 (Rattus norvegicus)6480464CTDQuetiapine Fumarate results in increased expression of SOD1 mRNAPMID:12111809 PMID:12752374
SOD1multiple interactionsISOSod1 (Mus musculus)6480464CTDQuetiapine Fumarate inhibits the reaction [Cuprizone results in decreased activity of SOD1 protein]PMID:18938062
SOD1multiple interactionsISOSod1 (Rattus norvegicus)6480464CTDQuetiapine Fumarate inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SOD1 mRNA]PMID:12752374
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