GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | SOD1 | decreases activity | EXP | | 6480464 | CTD | Ditiocarb results in decreased activity of SOD1 protein; Ditiocarb results in decreased activity of SOD1 protein mutant form | PMID:16681429 PMID:8279580 | SOD1 | increases expression | EXP | | 6480464 | CTD | Ditiocarb results in increased expression of SOD1 mRNA | PMID:8279580 | SOD1 | multiple interactions | EXP | | 6480464 | CTD | [[Paraquat co-treated with Ditiocarb] results in decreased activity of SOD1 protein] which results in increased expression of ICAM1 protein | PMID:10644010 | SOD1 | increases expression | ISO | Sod1 (Rattus norvegicus) | 6480464 | CTD | Ditiocarb results in increased expression of SOD1 protein | PMID:19467251 PMID:20452388 PMID:22874009 | SOD1 | multiple interactions | ISO | Sod1 (Mus musculus) | 6480464 | CTD | Ditiocarb inhibits the reaction [lactacystin affects the localization of SOD1 protein mutant form] | PMID:15034941 | |
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