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GENE - TERM ANNOTATION REPORT

RGD ID: 730824
Species: Homo sapiens
RGD Object: Gene
Symbol: GNAI1
Name: G protein subunit alpha i1
Acc ID: GO:0005834
Term: heterotrimeric G-protein complex
Definition: Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein.
Definition Source(s): ISBN:0198547684
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GNAI1part_ofIBACGD:CAL0000174954 or FB:FBgn0001122 or FB:FBgn0001123 or MGI:3588268 or PANTHER:PTN000026392 or PomBase:SPAC23H3.13c or Gnat1 (Rattus norvegicus) or Gnas (Rattus norvegicus) or Gna11 (Rattus norvegicus) or Gnaq (Rattus norvegicus) or SGD:S000001047 or TAIR:locus:2005529 or dictyBase:DDB_G0276267150520179GO_Central GO_REF:0000033
GNAI1part_ofTAS 150520179PINC PMID:3110783

PMID:3110783
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