GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ABCB1 | increases expression | EXP | | 6480464 | CTD | Beclomethasone results in increased expression of ABCB1 mRNA; Beclomethasone results in increased expression of ABCB1 protein | PMID:15370884 PMID:22464980 | ABCB1 | increases secretion | EXP | | 6480464 | CTD | ABCB1 protein results in increased secretion of Beclomethasone | PMID:22464980 | ABCB1 | multiple interactions | EXP | | 6480464 | CTD | Beclomethasone inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]; Beclomethasone inhibits the reaction [ABCB1 protein results in increased export of fluorexon]; Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Beclomethasone]; valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Beclomethasone] | PMID:16442095 PMID:22464980 | | ||||||||||||||||||||||
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