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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730822
Species: Mus musculus
RGD Object: Gene
Symbol: Mmp2
Name: matrix metallopeptidase 2
Acc ID: CHEBI:47977
Term: 2-amino-2-deoxy-D-glucopyranose
Definition: A D-glucosamine whose structure comprises D-glucopyranose having an amino substituent at position 2.
Chemical ID: MESH:D005944
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp2increases expressionISOMmp2 (Rattus norvegicus)6480464CTDGlucosamine results in increased expression of MMP2 mRNAPMID:17109745
Mmp2multiple interactionsISOMmp2 (Rattus norvegicus)6480464CTDIL1B promotes the reaction [Glucosamine results in increased expression of MMP2 mRNA]PMID:17109745
Mmp2multiple interactionsISOMMP2 (Homo sapiens)6480464CTDGlucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]PMID:17498959 PMID:19375915
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