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GENE - TERM ANNOTATION REPORT

RGD ID: 730821
Species: Homo sapiens
RGD Object: Gene
Symbol: MMP2
Name: matrix metallopeptidase 2
Acc ID: GO:0001666
Term: response to hypoxia
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
Definition Source(s): GOC:hjd
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MMP2 ISOMmp2 (Rattus norvegicus)9068941RGD PMID:16980344 REF_RGD_ID:1582594
MMP2involved_inIEAUniProtKB:P33434 or UniProtKB:P33436 or ensembl:ENSMUSP00000034187 or ensembl:ENSRNOP00000022679150520179Ensembl GO_REF:0000107
MMP2involved_inIBAMGI:97009 or PANTHER:PTN002565602 or Mmp2 (Rattus norvegicus)150520179GO_Central GO_REF:0000033
MMP2acts_upstream_of_or_withinISOMmp2 (Mus musculus)9068941MGI PMID:17382917

PMID:17382917
MMP2involved_inIEAPANTHER:PTHR10201:SF29150520179TreeGrafter GO_REF:0000118
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