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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730821
Species: Homo sapiens
RGD Object: Gene
Symbol: MMP2
Name: matrix metallopeptidase 2
Acc ID: CHEBI:34317
Term: 3,3',4,4',5-pentachlorobiphenyl
Definition: A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions.
Chemical ID: MESH:C023035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MMP2increases expressionEXP 6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MMP2 mRNAPMID:27663891 PMID:29947894 PMID:35618242
MMP2increases secretionISOMmp2 (Mus musculus)6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of MMP2 proteinPMID:27663891
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