Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 728891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gjb2
Name: gap junction protein, beta 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gjb2affects expressionEXP 6480464CTDbisphenol A affects the expression of GJB2 mRNAPMID:25181051 PMID:30903817
Gjb2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of GJB2 mRNAPMID:30816183 PMID:34947998
Gjb2increases expressionEXP 6480464CTDbisphenol A results in increased expression of GJB2 mRNAPMID:32145629
Gjb2decreases expressionISOGJB2 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of GJB2 mRNAPMID:30187510
Gjb2decreases expressionISOGjb2 (Mus musculus)6480464CTDbisphenol A results in decreased expression of GJB2 mRNAPMID:22687993 PMID:26063408 PMID:33221593
Gjb2decreases methylationISOGJB2 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of GJB2 genePMID:31601247
Gjb2increases expressionISOGjb2 (Mus musculus)6480464CTDbisphenol A results in increased expression of GJB2 mRNAPMID:30951980 PMID:32156529 PMID:34585602
Gjb2multiple interactionsISOGJB2 (Homo sapiens)6480464CTDFulvestrant inhibits the reaction [bisphenol A results in decreased expression of GJB2 mRNA]PMID:30187510
Gjb2multiple interactionsISOGjb2 (Mus musculus)6480464CTD[bisphenol A co-treated with Tretinoin] results in increased expression of GJB2 mRNAPMID:30951980
Go Back to source page   Continue to Ontology report