GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ace2 | decreases expression | EXP | | 6480464 | CTD | Glucose results in decreased expression of ACE2 mRNA | PMID:29211853 | Ace2 | multiple interactions | EXP | | 6480464 | CTD | NFE2L2 protein affects the reaction [Glucose results in decreased expression of ACE2 mRNA]; oltipraz inhibits the reaction [trigonelline inhibits the reaction [Glucose results in decreased expression of ACE2 mRNA]]; trigonelline inhibits the reaction [Glucose results in decreased expression of ACE2 mRNA] | PMID:29211853 | Ace2 | decreases expression | ISO | Ace2 (Mus musculus) | 6480464 | CTD | Glucose results in decreased expression of ACE2 protein | PMID:29266779 | Ace2 | multiple interactions | ISO | Ace2 (Mus musculus) | 6480464 | CTD | CEBPB protein inhibits the reaction [Glucose results in decreased expression of ACE2 protein]; Glucose inhibits the reaction [CEBPB protein binds to ACE2 promoter]; Valsartan inhibits the reaction [Glucose results in decreased expression of ACE2 protein] | PMID:29266779 | |
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