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GENE - TERM ANNOTATION REPORT

RGD ID: 727962
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pigw
Name: phosphatidylinositol glycan anchor biosynthesis, class W
Acc ID: GO:0006506
Term: GPI anchor biosynthetic process
Definition: The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
Definition Source(s): GOC:go_curators, ISBN:0198547684
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pigwinvolved_inIBACGD:CAL0000196562 or PANTHER:PTN000464299 or PomBase:SPAC144.10c or SGD:S000003627 or UniProtKB:Q873N11600115GO_CentralGO_REF:0000033

GO_REF:0000033
Pigwinvolved_inIEAUniPathway:UPA001961600115UniProtGO_REF:0000041

GO_REF:0000041
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