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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727892
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdkn1c
Name: cyclin-dependent kinase inhibitor 1C
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdkn1caffects expressionEXP 6480464CTDbisphenol A affects the expression of CDKN1C mRNAPMID:25181051
Cdkn1cdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of CDKN1C mRNAPMID:24988533 PMID:30816183 PMID:32145629 PMID:34947998
Cdkn1cincreases expressionEXP 6480464CTDbisphenol A results in increased expression of CDKN1C mRNAPMID:18180321
Cdkn1cdecreases expressionISOCdkn1c (Mus musculus)6480464CTDbisphenol A results in decreased expression of CDKN1C mRNAPMID:23593014
Cdkn1cincreases expressionISOCDKN1C (Homo sapiens)6480464CTDbisphenol A results in increased expression of CDKN1C proteinPMID:26027920
Cdkn1cincreases expressionISOCdkn1c (Mus musculus)6480464CTDbisphenol A results in increased expression of CDKN1C mRNAPMID:32156529 PMID:37105096
Cdkn1cincreases methylationISOCDKN1C (Homo sapiens)6480464CTDbisphenol A results in increased methylation of CDKN1C genePMID:28582417
Cdkn1cmultiple interactionsISOCDKN1C (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CDKN1C mRNAPMID:28628672
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