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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rela
Name: RELA proto-oncogene, NF-kB subunit
Acc ID: CHEBI:50692
Term: mifepristone
Definition: A 3-oxo steroid that has formula 429.59374.
Chemical ID: MESH:D015735
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Relamultiple interactionsEXP 6480464CTD[Mifepristone co-treated with Paraquat] results in increased expression of RELA protein; NFE2L2 protein inhibits the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of RELA protein]PMID:24812154
Relamultiple interactionsISORELA (Homo sapiens)6480464CTDMifepristone inhibits the reaction [Dexamethasone results in decreased phosphorylation of and affects the localization of RELA protein]; Mifepristone inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]]PMID:15358673 PMID:32619553
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