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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rela
Name: RELA proto-oncogene, NF-kB subunit
Acc ID: CHEBI:26197
Term: polyphosphates
Definition: Any phosphate that is a salt or an ester of polyphosphoric acid or its chalcogen analogues.
Chemical ID: MESH:D011122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Relaincreases activityISORELA (Homo sapiens)6480464CTDPolyphosphates results in increased activity of RELA proteinPMID:27458080 PMID:27481191
Relamultiple interactionsISORELA (Homo sapiens)6480464CTDdabrafenib inhibits the reaction [Polyphosphates results in increased activity of RELA protein]; Diketopiperazines inhibits the reaction [Polyphosphates results in increased activity of RELA protein]PMID:27458080 PMID:27481191
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