GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcc3 | affects expression | ISO | ABCC3 (Homo sapiens) | 6480464 | CTD | Methotrexate affects the expression of ABCC3 mRNA | PMID:23897011 | Abcc3 | affects response to substance | ISO | ABCC3 (Homo sapiens) | 6480464 | CTD | ABCC3 gene mutant form affects the susceptibility to Methotrexate; ABCC3 gene SNP affects the susceptibility to Methotrexate | PMID:19426680 PMID:22859359 | Abcc3 | decreases response to substance | ISO | Abcc3 (Mus musculus) | 6480464 | CTD | ABCC3 mRNA results in decreased susceptibility to Methotrexate | PMID:16918715 | |
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