Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - TERM ANNOTATION REPORT

RGD ID: 71049
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hnmt
Name: histamine N-methyltransferase
Acc ID: DOID:2841
Term: asthma
Definition: A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing. (DO)
Definition Source(s): http://www.nhlbi.nih.gov/health/dci/Diseases/Asthma/Asthma_WhatIs.html "DO" "DO", https://www.ncbi.nlm.nih.gov/books/NBK430901/ "DO" "DO", https://www.ncbi.nlm.nih.gov/books/NBK7223/ "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hnmt ISOHNMT (Homo sapiens)5128881RGD  
Hnmt ISOHNMT (Homo sapiens)5128883RGD  
Hnmtno_associationISOHNMT (Homo sapiens)5128885RGD  
Hnmtno_associationISOHNMT (Homo sapiens)5128887RGD  
Hnmtno_associationISOHNMT (Homo sapiens)5128888RGD  
Hnmt ISOHNMT (Homo sapiens)7240710OMIM  
Hnmt ISOHNMT (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:17651147
Hnmt ISOHNMT (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Asthma, susceptibility toPMID:10752634 PMID:10803682 PMID:16205835 PMID:25741868
Go Back to source page   Continue to Ontology report