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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71016
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp8b1
Name: cytochrome P450 family 8 subfamily B member 1
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp8b1multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP8B1 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP8B1 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP8B1 mRNAPMID:18253720 PMID:18544905 PMID:28943392
Cyp8b1decreases expressionISOCyp8b1 (Mus musculus)6480464CTDDiethylnitrosamine results in decreased expression of CYP8B1 mRNAPMID:24535843
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