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GENE - TERM ANNOTATION REPORT

RGD ID: 71010
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ascl1
Name: achaete-scute family bHLH transcription factor 1
Acc ID: GO:0003700
Term: DNA-binding transcription factor activity
Definition: A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
Definition Source(s): GOC:txnOH-2018
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ascl1enablesISOAscl1 (Mus musculus)1624291RGD MGI:5897542 PMID:24243019 PMID:17141158

MGI:5897542 PMID:17141158 PMID:24243019
Ascl1enablesISOASCL1 (Homo sapiens)1624291RGD PMID:10903890

PMID:10903890
Ascl1enablesISSUniProtKB:Q020671600115UniProtGO_REF:0000024

GO_REF:0000024
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