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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71000
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Myh10
Name: myosin heavy chain 10
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Myh10decreases expressionEXP 6480464CTDEstradiol results in decreased expression of MYH10 mRNAPMID:32145629
Myh10affects expressionISOMYH10 (Homo sapiens)6480464CTDEstradiol affects the expression of MYH10 mRNAPMID:22574217
Myh10multiple interactionsISOMYH10 (Homo sapiens)6480464CTDEstradiol affects the localization of and results in increased expression of and results in increased phosphorylation of and affects the activity of MYH10 protein; Estradiol inhibits the reaction [MYH10 protein binds to MYH10 protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of MYH10 protein]; fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of MYH10 protein]; Tamoxifen inhibits the reaction [Estradiol results in increased expression of MYH10 protein]PMID:16901965
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