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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70988
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akap12
Name: A-kinase anchoring protein 12
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akap12affects expressionEXP 6480464CTDbisphenol A affects the expression of AKAP12 mRNAPMID:25181051
Akap12decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of AKAP12 mRNAPMID:12075121 PMID:30816183 PMID:32145629 PMID:32528016 PMID:34947998
Akap12affects expressionISOAKAP12 (Homo sapiens)6480464CTDbisphenol A affects the expression of AKAP12 mRNA; bisphenol A affects the expression of AKAP12 proteinPMID:30903817 PMID:37567409
Akap12decreases expressionISOAKAP12 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of AKAP12 mRNA; bisphenol A results in decreased expression of AKAP12 proteinPMID:29275510 PMID:34186270
Akap12decreases expressionISOAkap12 (Mus musculus)6480464CTDbisphenol A results in decreased expression of AKAP12 mRNAPMID:25594700 PMID:33221593
Akap12multiple interactionsISOAKAP12 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of AKAP12 mRNAPMID:28628672
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