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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70971
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hamp
Name: hepcidin antimicrobial peptide
Acc ID: CHEBI:78291
Term: iron dextran
Definition: Please consider adding concept for iron dextran. CAS# 9004-66-4. Thank you.
Chemical ID: MESH:D007505
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hampincreases expressionISOHamp (Mus musculus)6480464CTDIron-Dextran Complex results in increased expression of HAMP mRNAPMID:27095094
Hampmultiple interactionsISOHamp (Mus musculus)6480464CTD[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of HAMP mRNA; Diltiazem promotes the reaction [Iron-Dextran Complex results in increased expression of HAMP mRNA]; Nimodipine promotes the reaction [Iron-Dextran Complex results in increased expression of HAMP mRNA]; Verapamil promotes the reaction [Iron-Dextran Complex results in increased expression of HAMP mRNA]PMID:27095094 PMID:33393188
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