GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sulf1 | decreases expression | EXP | | 6480464 | CTD | Silicon Dioxide results in decreased expression of SULF1 protein | PMID:29673857 | Sulf1 | decreases expression | ISO | SULF1 (Homo sapiens) | 6480464 | CTD | Silicon Dioxide results in decreased expression of SULF1 mRNA; Silicon Dioxide results in decreased expression of SULF1 protein | PMID:22300531 PMID:25351596 PMID:29673857 | Sulf1 | increases expression | ISO | SULF1 (Homo sapiens) | 6480464 | CTD | Silicon Dioxide analog results in increased expression of SULF1 mRNA | PMID:23806026 | Sulf1 | increases response to substance | ISO | SULF1 (Homo sapiens) | 6480464 | CTD | SULF1 mRNA results in increased susceptibility to Silicon Dioxide | PMID:29673857 | Sulf1 | multiple interactions | ISO | SULF1 (Homo sapiens) | 6480464 | CTD | [SULF1 mRNA results in increased susceptibility to Silicon Dioxide] which results in increased expression of ACTA2 mRNA; [SULF1 mRNA results in increased susceptibility to Silicon Dioxide] which results in increased expression of BIRC3 mRNA; [SULF1 mRNA results in increased susceptibility to Silicon Dioxide] which results in increased expression of CCND1 mRNA; [SULF1 mRNA results in increased susceptibility to Silicon Dioxide] which results in increased expression of COL1A1 mRNA; [SULF1 mRNA results in increased susceptibility to Silicon Dioxide] which results in increased expression of JUN mRNA; [SULF1 mRNA results in increased susceptibility to Silicon Dioxide] which results in increased expression of SERPINE1 mRNA; [SULF1 mRNA results in increased susceptibility to Silicon Dioxide] which results in increased expression of VEGFA mRNA; SULF1 mRNA promotes the reaction [Silicon Dioxide results in increased expression of IL24 mRNA]; SULF1 mRNA promotes the reaction [Silicon Dioxide results in increased expression of MMP1 mRNA] | PMID:29673857 | |
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