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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708541
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ugt2b1
Name: UDP glucuronosyltransferase 2 family, polypeptide B1
Acc ID: CHEBI:76604
Term: MeIQx
Definition: An imidazoquinoxaline that is 3H-imidazo[4,5-f]quinoxaline substituted at positions 3 and 8 by methyl groups and at position 2 by an amino group. A mutagenic compound found in cooked beef.
Chemical ID: MESH:C036990
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ugt2b1multiple interactionsISOUgt2b1 (Mus musculus)6480464CTD[flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in decreased expression of UGT2B1 mRNAPMID:23681119
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