GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hpcal1 | multiple interactions | EXP | | 6480464 | CTD | [[Testosterone co-treated with Estradiol] affects the reaction [estradiol-17 beta-benzoate results in increased methylation of HPCAL1 promoter]] which affects the expression of HPCAL1 protein; [[Testosterone co-treated with Estradiol] results in increased methylation of HPCAL1 promoter] which results in decreased expression of HPCAL1 mRNA; [Testosterone co-treated with Estradiol] affects the reaction [estradiol-17 beta-benzoate results in increased methylation of HPCAL1 promoter]; [Testosterone co-treated with Estradiol] results in increased methylation of HPCAL1 promoter | PMID:22109888 | Hpcal1 | affects expression | ISO | HPCAL1 (Homo sapiens) | 6480464 | CTD | Estradiol affects the expression of HPCAL1 mRNA | PMID:22574217 | Hpcal1 | multiple interactions | ISO | HPCAL1 (Homo sapiens) | 6480464 | CTD | [Estradiol co-treated with TGFB1 protein] results in decreased expression of HPCAL1 mRNA | PMID:30165855 | | ||||||||||||||||||||||
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