GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | LPL | affects expression | EXP | | 6480464 | CTD | bisphenol A affects the expression of LPL mRNA | PMID:32175033 | LPL | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of LPL mRNA; bisphenol A results in decreased expression of LPL protein | PMID:22662114 PMID:31675489 PMID:34186270 | LPL | decreases methylation | EXP | | 6480464 | CTD | bisphenol A results in decreased methylation of LPL gene | PMID:31601247 | LPL | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of LPL mRNA; bisphenol A results in increased expression of LPL protein | PMID:23090578 PMID:25143472 PMID:29721103 | LPL | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of LPL mRNA; [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of LPL protein; [bisphenol A co-treated with Fulvestrant] affects the methylation of LPL gene; [bisphenol A results in decreased expression of LPL mRNA] which affects the abundance of Triglycerides; [Vitamin D co-treated with bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] affects the expression of LPL mRNA | PMID:22662114 PMID:31601247 PMID:33836827 PMID:35736896 | LPL | decreases expression | ISO | Lpl (Mus musculus) | 6480464 | CTD | bisphenol A results in decreased expression of LPL mRNA | PMID:27502578 PMID:30133442 | LPL | decreases expression | ISO | Lpl (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in decreased expression of LPL mRNA | PMID:24105817 PMID:25181051 PMID:28657538 PMID:30816183 PMID:31129395 PMID:32145629 PMID:32528016 PMID:34947998 | LPL | increases expression | ISO | Lpl (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of LPL mRNA | PMID:15659569 PMID:30566610 PMID:33221593 PMID:35341816 PMID:37755785 | LPL | increases expression | ISO | Lpl (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased expression of LPL mRNA | PMID:20019905 PMID:25748669 PMID:34165232 | LPL | multiple interactions | ISO | Lpl (Mus musculus) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of LPL mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [[bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of LPL mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [[bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of LPL protein]; [bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of LPL mRNA; [bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of LPL mRNA; [bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of LPL protein; [Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of LPL mRNA; bisphenol A inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of LPL mRNA] | PMID:15659569 PMID:22197818 PMID:27273607 PMID:30665118 PMID:30722647 | LPL | multiple interactions | ISO | Lpl (Rattus norvegicus) | 6480464 | CTD | lithospermate B inhibits the reaction [bisphenol A results in increased expression of LPL mRNA] | PMID:34165232 | |
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