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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70836
Species: Homo sapiens
RGD Object: Gene
Symbol: LPL
Name: lipoprotein lipase
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LPLdecreases expressionEXP 6480464CTDresveratrol results in decreased expression of LPL mRNAPMID:16901463
LPLdecreases activityISOLpl (Rattus norvegicus)6480464CTDresveratrol results in decreased activity of LPL proteinPMID:21569266 PMID:24012391
LPLdecreases expressionISOLpl (Mus musculus)6480464CTDresveratrol metabolite results in decreased expression of LPL mRNA; resveratrol results in decreased expression of LPL mRNAPMID:18555852 PMID:22945685 PMID:24722352 PMID:25338179
LPLdecreases expressionISOLpl (Rattus norvegicus)6480464CTDresveratrol results in decreased expression of LPL mRNAPMID:23848300 PMID:24012391
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