GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | LPL | affects expression | EXP | | 6480464 | CTD | Estradiol affects the expression of LPL mRNA | PMID:14699072 | LPL | decreases expression | EXP | | 6480464 | CTD | Estradiol results in decreased expression of LPL mRNA | PMID:31646340 | LPL | multiple interactions | EXP | | 6480464 | CTD | [Estradiol binds to ESR2 protein] which results in increased expression of LPL mRNA; [Estradiol co-treated with TGFB1 protein] results in decreased expression of LPL mRNA | PMID:20404318 PMID:30165855 | LPL | decreases expression | ISO | Lpl (Mus musculus) | 6480464 | CTD | Estradiol results in decreased expression of LPL mRNA | PMID:16643890 | LPL | decreases expression | ISO | Lpl (Rattus norvegicus) | 6480464 | CTD | Estradiol results in decreased expression of LPL mRNA | PMID:32145629 | LPL | increases expression | ISO | Lpl (Mus musculus) | 6480464 | CTD | Estradiol results in increased expression of LPL mRNA | PMID:17974624 | LPL | increases expression | ISO | Lpl (Rattus norvegicus) | 6480464 | CTD | Estradiol results in increased expression of LPL mRNA | PMID:17522070 | LPL | multiple interactions | ISO | Lpl (Mus musculus) | 6480464 | CTD | ESR1 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]; ESR2 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]; fulvestrant inhibits the reaction [ESR1 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]]; fulvestrant inhibits the reaction [ESR2 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]]; fulvestrant inhibits the reaction [Estradiol results in increased expression of LPL mRNA]; Progesterone inhibits the reaction [ESR1 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]]; Progesterone inhibits the reaction [ESR2 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]]; Progesterone inhibits the reaction [Estradiol results in increased expression of LPL mRNA] | PMID:17974624 | | ||||||||||||||||||||||
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