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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708351
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kdm3a
Name: lysine demethylase 3A
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kdm3aincreases expressionISOKDM3A (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of KDM3A mRNA; Oxygen deficiency results in increased expression of KDM3A proteinPMID:20042640 PMID:20881000 PMID:23546878 PMID:24236059 PMID:25596134 PMID:26516004 PMID:34826399
Kdm3aincreases expressionISOKdm3a (Mus musculus)6480464CTDOxygen deficiency results in increased expression of KDM3A mRNA; Oxygen deficiency results in increased expression of KDM3A proteinPMID:20880076 PMID:20881000
Kdm3amultiple interactionsISOKDM3A (Homo sapiens)6480464CTDOxygen deficiency promotes the reaction [HIF3A protein binds to KDM3A promoter]; Oxygen deficiency promotes the reaction [KDM3A protein binds to SPRY2 promoter]PMID:20881000 PMID:34826399
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