GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IGF1 | affects expression | ISO | Igf1 (Rattus norvegicus) | 6480464 | CTD | Caffeine affects the expression of IGF1 protein | PMID:29343424 | IGF1 | decreases activity | ISO | Igf1 (Rattus norvegicus) | 6480464 | CTD | Caffeine results in decreased activity of IGF1 protein | PMID:24239806 | IGF1 | decreases expression | ISO | Igf1 (Rattus norvegicus) | 6480464 | CTD | Caffeine results in decreased expression of IGF1 mRNA; Caffeine results in decreased expression of IGF1 protein | PMID:22583948 PMID:29343424 PMID:29966748 PMID:30528684 | IGF1 | decreases secretion | ISO | Igf1 (Mus musculus) | 6480464 | CTD | Caffeine results in decreased secretion of IGF1 protein | PMID:1995187 | IGF1 | multiple interactions | ISO | Igf1 (Mus musculus) | 6480464 | CTD | [Caffeine co-treated with bisphenol A] results in decreased expression of IGF1 mRNA | PMID:31756439 | |
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