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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70500
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk1
Name: mitogen activated protein kinase 1
Acc ID: CHEBI:34205
Term: 2,2',4,5-tetrachlorobiphenyl
Definition: A tetrachlorobiphenyl that is biphenyl in which the hydrogens at positions 2, 4, 5, and 2' are replaced by chlorines.
Chemical ID: MESH:C042128
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk1increases phosphorylationISOMAPK1 (Homo sapiens)6480464CTD2,4,4',5-tetrachlorobiphenyl results in increased phosphorylation of MAPK1 proteinPMID:19751709
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