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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70499
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Birc5
Name: baculoviral IAP repeat-containing 5
Acc ID: CHEBI:48607
Term: lithium chloride
Definition: A metal chloride salt with a Li(+) counterion.
Chemical ID: MESH:D018021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Birc5multiple interactionsEXP 6480464CTDLithium Chloride inhibits the reaction [manganese chloride results in decreased expression of BIRC5 mRNA]PMID:24464479
Birc5increases expressionISOBIRC5 (Homo sapiens)6480464CTDLithium Chloride results in increased expression of BIRC5 proteinPMID:35985571
Birc5multiple interactionsISOBIRC5 (Homo sapiens)6480464CTDLithium Chloride inhibits the reaction [hydroquinone results in decreased expression of BIRC5 protein]; Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased expression of BIRC5 protein]PMID:28886972 PMID:35985571
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