GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | BAX | affects localization | EXP | | 6480464 | CTD | Acrolein affects the localization of BAX protein | PMID:19596284 | BAX | increases expression | EXP | | 6480464 | CTD | Acrolein results in increased expression of BAX mRNA; Acrolein results in increased expression of BAX protein | PMID:33421550 PMID:34958888 | BAX | multiple interactions | EXP | | 6480464 | CTD | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of BAX mRNA; [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of BAX mRNA | PMID:32699268 | BAX | increases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | Acrolein results in increased expression of BAX protein | PMID:24376112 | BAX | increases expression | ISO | Bax (Rattus norvegicus) | 6480464 | CTD | Acrolein results in increased expression of BAX mRNA; Acrolein results in increased expression of BAX protein | PMID:29414845 | BAX | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | capsazepine inhibits the reaction [Acrolein results in increased expression of BAX protein]; Glutathione inhibits the reaction [Acrolein results in increased expression of BAX protein] | PMID:24376112 | BAX | multiple interactions | ISO | Bax (Rattus norvegicus) | 6480464 | CTD | 3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in increased expression of BAX mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in increased expression of BAX protein]; [Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of BAX protein; Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX mRNA]; Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX protein]; oleuropein inhibits the reaction [Acrolein results in increased expression of BAX mRNA]; oleuropein inhibits the reaction [Acrolein results in increased expression of BAX protein]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of BAX protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX mRNA]]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX protein]] | PMID:29414845 | | ||||||||||||||||||||||
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